Nanoparticle-based targeted drug delivery

Computational Modeling of Nanoparticle Targeted Drug Delivery

Nanomedicine is a promising application of nanotechnology in medicine, which can drastically improve drug delivery efficiency through targeted delivery. However, characterization of the nanoparticle targeted delivery process under vascular environment is very challenging due to the small scale of nanoparticles and the complex in vivo vascular system. To understand such complicated system, vario...

Advances in Targeted Drug Delivery

Advances in Targeted Drug Delivery

Nanoparticle-Based Brain Targeted Delivery Systems

Presenting a very dismal prognosis, glioblastomas present as one of the most malignant brain tumors [1]. In addition to its low prognosis, glioblastomas account for ~70% of all astrocytic and oligodendroglial tumors, making this one of the most common types of brain tumors [1]. Through the mutations of multiple pro-oncogenic genes, primary glioblastomas develop as other neoplasms but present as...

Mathematical Analysis of Drug Release for Gastrointestinal Targeted Delivery Using β-Lactoglobulin Nanoparticle

To answer challenge of targeted and controlled drug release in oral delivery various materials were studied by different methods. In the present paper, controlled metal based drug (Pd(II) complex) release manner of β‑Lactoglobulin (β-LG) nanoparticles was investigated using mathematical drug release model in order to design and production of a new oral drug delivery system for gastrointestinal ...